Human Artificial Chromosomes with Alpha Satellite-Based De Novo Centromeres Show Increased Frequency of Nondisjunction and Anaphase Lag

Human artificial chromosomes have been used to model requirements for human chromosome segregation and to explore the nature of sequences competent for centromere function. Normal human centromeres require specialized chromatin that consists of alpha satellite DNA complexed with epigenetically modif...

詳細記述

書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Rudd, M. Katharine, Mays, Robert W., Schwartz, Stuart, Willard, Huntington F.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 2003
主題:	DNA Dynamics and Chromosome Structure
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207596/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14560014/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7689-7697.2003
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