Human Artificial Chromosomes with Alpha Satellite-Based De Novo Centromeres Show Increased Frequency of Nondisjunction and Anaphase Lag

Human artificial chromosomes have been used to model requirements for human chromosome segregation and to explore the nature of sequences competent for centromere function. Normal human centromeres require specialized chromatin that consists of alpha satellite DNA complexed with epigenetically modif...

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Bibliografski detalji

Izdano u:	Mol Cell Biol
Glavni autori:	Rudd, M. Katharine, Mays, Robert W., Schwartz, Stuart, Willard, Huntington F.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 2003
Teme:	DNA Dynamics and Chromosome Structure
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207596/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14560014/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7689-7697.2003
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