Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism

Ceramide is generated in response to numerous stress-inducing stimuli and has been implicated in the regulation of diverse cellular responses, including cell death, differentiation, and insulin sensitivity. Recent evidence indicates that ceramide may regulate these responses by inhibiting the stimul...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Powell, Darren J., Hajduch, Eric, Kular, Gursant, Hundal, Harinder S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2003
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14560023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7794-7808.2003
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