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Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism

Ceramide is generated in response to numerous stress-inducing stimuli and has been implicated in the regulation of diverse cellular responses, including cell death, differentiation, and insulin sensitivity. Recent evidence indicates that ceramide may regulate these responses by inhibiting the stimul...

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Udgivet i:Mol Cell Biol
Principais autores: Powell, Darren J., Hajduch, Eric, Kular, Gursant, Hundal, Harinder S.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207567/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14560023/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7794-7808.2003
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