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Surface-scanning mutational analysis of protein arginine methyltransferase 1: roles of specific amino acids in methyltransferase substrate specificity, oligomerization, and coactivator function

Protein arginine methyltransferase 1 (PRMT1) is an arginine-specific protein methyltransferase that methylates a number of proteins involved in transcription and other aspects of RNA metabolism. Its role as a transcriptional coactivator for nuclear receptors involves its ability to bind to other coa...

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Detalhes bibliográficos
Main Authors: Lee, David Y., Ianculescu, Irina, Purcell, Daniel, Zhang, Xing, Cheng, Xiaodong, Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075475/
https://ncbi.nlm.nih.gov/pubmed/17426288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2006-0389
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