Synergy among Nuclear Receptor Coactivators: Selective Requirement for Protein Methyltransferase and Acetyltransferase Activities

Hormone-activated nuclear receptors (NR) bind to specific regulatory DNA elements associated with their target genes and recruit coactivator proteins to remodel chromatin structure, recruit RNA polymerase, and activate transcription. The p160 coactivators (e.g., SRC-1, GRIP1, and ACTR) bind directly...

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Detalhes bibliográficos
Main Authors: Lee, Young-Ho, Koh, Stephen S., Zhang, Xing, Cheng, Xiaodong, Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133819/
https://ncbi.nlm.nih.gov/pubmed/11997499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3621-3632.2002
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