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Substrate specificity of mammalian N-terminal α-amino methyltransferase

N-terminal methylation of free α-amino-groups is a post-translational modification of proteins that has been known for 30 years but has been very little studied. In this modification, the initiating M residue is cleaved and the exposed α-amino group is mono- di- or trimethylated by NRMT, a recently...

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Detalhes bibliográficos
Main Authors: Petkowski, Janusz J., Schaner Tooley, Christine E., Anderson, Lissa C., Shumilin, Igor A., Balsbaugh, Jeremy L., Shabanowitz, Jeffrey, Hunt, Donald F., Minor, Wladek, Macara, Ian G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447998/
https://ncbi.nlm.nih.gov/pubmed/22769851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300278f
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