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N-terminal α-methylation of RCC1 is necessary for stable chromatin association and normal mitosis
Regulator of chromatin condensation 1 (RCC1) is the only known guanine nucleotide-exchange factor for the Ran GTPase and has pivotal roles in nucleo-cytoplasmic transport, mitosis, and nuclear-envelope assembly(1). RCC1 associates dynamically with chromatin through binding to histones H2A and/or H2B...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624279/ https://ncbi.nlm.nih.gov/pubmed/17435751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1572 |
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