N-terminal α-methylation of RCC1 is necessary for stable chromatin association and normal mitosis

Regulator of chromatin condensation 1 (RCC1) is the only known guanine nucleotide-exchange factor for the Ran GTPase and has pivotal roles in nucleo-cytoplasmic transport, mitosis, and nuclear-envelope assembly(1). RCC1 associates dynamically with chromatin through binding to histones H2A and/or H2B...

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Bibliografiska uppgifter
I publikationen:Nat Cell Biol
Huvudupphovsmän: Chen, Ting, Muratore, Tara L., Schaner-Tooley, Christine E., Shabanowitz, Jeffrey, Hunt, Donald F., Macara, Ian G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624279/
https://ncbi.nlm.nih.gov/pubmed/17435751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1572
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