Nitroxyl increases force development in rat cardiac muscle

Donors of nitroxyl (HNO), the reduced congener of nitric oxide (NO), exert positive cardiac inotropy/lusitropy in vivo and in vitro, due in part to their enhancement of Ca(2+) cycling into and out of the sarcoplasmic reticulum. Here we tested whether the cardiac action of HNO further involves change...

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Bibliographic Details
Main Authors: Dai, Tieying, Tian, Ye, Tocchetti, Carlo Gabriele, Katori, Tatsuo, Murphy, Anne M, Kass, David A, Paolocci, Nazareno, Gao, Wei Dong
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2007
Subjects:
Cardiovascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075441/
https://ncbi.nlm.nih.gov/pubmed/17331988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.129254
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