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A hydrophobic element secures S4 voltage sensor in position in resting Shaker K(+) channels

The S4 transmembrane α-helix in voltage-gated channels contains several regularly spaced basic amino acid residues that could be protonated and moved across the membrane electric field in response to membrane potential changes. The translocation of the charge-carrying S4 transduces membrane voltage...

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Autori principali: Yang, Ya-Chin, Own, Chia-Jen, Kuo, Chung-Chin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075241/
https://ncbi.nlm.nih.gov/pubmed/17412765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.131490
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