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Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K(+) channel voltage sensor domain

Membrane-embedded voltage-sensor domains in voltage-dependent potassium channels (K(v) channels) contain an impressive number of charged residues. How can such highly charged protein domains be efficiently inserted into biological membranes? In the plant K(v) channel KAT1, the S2, S3, and S4 transme...

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Detalhes bibliográficos
Main Authors: Zhang, Liyan, Sato, Yoko, Hessa, Tara, von Heijne, Gunnar, Lee, Jong-Kook, Kodama, Itsuo, Sakaguchi, Masao, Uozumi, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899110/
https://ncbi.nlm.nih.gov/pubmed/17488813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611007104
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