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Constraints on Voltage Sensor Movement in the Shaker K(+) Channel

In nerve and muscle cells, the voltage-gated opening and closing of cation-selective ion channels is accompanied by the translocation of 12–14 elementary charges across the membrane's electric field. Although most of these charges are carried by residues in the S4 helix of the gating module of...

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Detalhes bibliográficos
Main Authors: Darman, Rachel B., Ivy, Allison A., Ketty, Vina, Blaustein, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151604/
https://ncbi.nlm.nih.gov/pubmed/17101817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609624
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