Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer

BACKGROUND: Urodele amphibians like the axolotl are unique among vertebrates in their ability to regenerate and their resistance to develop cancers. It is unknown whether these traits are linked at the molecular level. RESULTS: Blocking p53 signaling in axolotls using the p53 inhibitor, pifithrin-α,...

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Autors principals: Villiard, Éric, Brinkmann, Henner, Moiseeva, Olga, Mallette, Frédérick A, Ferbeyre, Gerardo, Roy, Stéphane
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072957/
https://ncbi.nlm.nih.gov/pubmed/17903248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-180
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