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Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor
The mechanism by which the androgen receptor (AR) distinguishes between agonist and antagonist ligands is poorly understood. AR antagonists are currently used to treat prostate cancer. However, mutations commonly develop in patients that convert these compounds to agonists. Recently, our laboratory...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2072880/ https://ncbi.nlm.nih.gov/pubmed/16129672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M507464200 |
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