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In Vitro and in Vivo Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring

We recently reported two nonsteroidal androgen receptor (AR) ligands that demonstrate tissue-selective pharmacological activity, identifying these S-3-(phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide analogs as the first members of a new class of drugs known as selectiv...

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Detalhes bibliográficos
Main Authors: Chen, Jiyun, Hwang, Dong Jin, Chung, Kiwon, Bohl, Casey E., Fisher, Scott J., Miller, Duane D., Dalton, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2121105/
https://ncbi.nlm.nih.gov/pubmed/16166218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2005-0732
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