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Structural basis for antagonism and resistance of bicalutamide in prostate cancer

Carcinoma of the prostate is the most commonly diagnosed cancer in men. The current pharmacological treatment of choice for progressive androgen-dependent prostate cancer is the nonsteroidal antiandrogen, bicalutamide, either as monotherapy or with adjuvant castration or luteinizing hormone-releasin...

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Bibliografiske detaljer
Main Authors: Bohl, Casey E., Gao, Wenqing, Miller, Duane D., Bell, Charles E., Dalton, James T.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087923/
https://ncbi.nlm.nih.gov/pubmed/15833816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500381102
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