FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type.

FK-506-binding proteins (FKBPs), which in T cells are supposed to mediate the immunosuppressive effects of the compounds FK-506 and rapamycin, have been isolated from Streptomyces chrysomallus, S. hygroscopicus subsp. ascomyceticus, and S. hygroscopicus. The latter two strains are producers of ascom...

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Vydáno v:	J Bacteriol
Hlavní autoři:	Pahl, A, Keller, U
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1381710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.18.5888-5894.1992
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