FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type.
FK-506-binding proteins (FKBPs), which in T cells are supposed to mediate the immunosuppressive effects of the compounds FK-506 and rapamycin, have been isolated from Streptomyces chrysomallus, S. hygroscopicus subsp. ascomyceticus, and S. hygroscopicus. The latter two strains are producers of ascom...
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| Publicat a: | J Bacteriol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1381710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.18.5888-5894.1992 |
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