FK-506-binding proteins from streptomycetes producing immunosuppressive macrolactones of the FK-506 type.
FK-506-binding proteins (FKBPs), which in T cells are supposed to mediate the immunosuppressive effects of the compounds FK-506 and rapamycin, have been isolated from Streptomyces chrysomallus, S. hygroscopicus subsp. ascomyceticus, and S. hygroscopicus. The latter two strains are producers of ascom...
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| Publié dans: | J Bacteriol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1381710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.18.5888-5894.1992 |
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