Regulation of Cdc2/Cyclin B Activation in Xenopus Egg Extracts via Inhibitory Phosphorylation of Cdc25C Phosphatase by Ca(2+)/Calmodium-dependent Kinase II
Activation of Cdc2/cyclin B kinase and entry into mitosis requires dephosphorylation of inhibitory sites on Cdc2 by Cdc25 phosphatase. In vertebrates, Cdc25C is inhibited by phosphorylation at a single site targeted by the checkpoint kinases Chk1 and Cds1/Chk2 in response to DNA damage or replicatio...
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| Publicado en: | Mol Biol Cell |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Cell Biology
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-02-0061 |
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