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G(2) arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A

Xenopus oocytes, which are arrested in G(2) of meiosis I, contain complexes of cyclin B–cdc2 (M phase-promoting factor) that are kept repressed by inhibitory phosphorylations on cdc2 at Thr-14 and Tyr-15. Progesterone induces a cytoplasmic signaling pathway that leads to activation of cdc25, the pho...

詳細記述

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書誌詳細
主要な著者: Duckworth, Brian C., Weaver, Jennifer S., Ruderman, Joan V.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC139223/
https://ncbi.nlm.nih.gov/pubmed/12477927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222661299
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