G(2) arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A
Xenopus oocytes, which are arrested in G(2) of meiosis I, contain complexes of cyclin B–cdc2 (M phase-promoting factor) that are kept repressed by inhibitory phosphorylations on cdc2 at Thr-14 and Tyr-15. Progesterone induces a cytoplasmic signaling pathway that leads to activation of cdc25, the pho...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477927/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222661299 |
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