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Mitotic Effects of a Constitutively Active Mutant of the Xenopus Polo-Like Kinase Plx1

During mitosis the Xenopus polo-like kinase 1 (Plx1) plays key roles in the activation of Cdc25C, in spindle assembly, and in cyclin B degradation. Previous work has shown that the activation of Plx1 requires phosphorylation on serine and threonine residues. In the present work, we demonstrate that...

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Detalhes bibliográficos
Main Authors: Qian, Yue-Wei, Erikson, Eleanor, Maller, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84996/
https://ncbi.nlm.nih.gov/pubmed/10567586
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