Azetidinones as Vasopressin V1a Antagonists

The azetidinone LY307174 (1) was identified as a screening lead for the vasopressin V1a receptor (IC(50) 45 nM at the human V1a receptor) based on molecular similarity to ketoconazole (2), a known antagonist of the luteinizing hormone releasing hormone receptor. Structure-activity relationships for...

詳細記述

保存先:
書誌詳細
主要な著者: Guillon, Christophe D., Koppel, Gary A., Brownstein, Michael J., Chaney, Michael O., Ferris, Craig F., Lu, Shi-fang, Fabio, Karine M., Miller, Marvin J., Heindel, Ned D., Hunden, David C., Cooper, Robin D. G., Kaldor, Stephen W., Skelton, Jeffrey J., Dressman, Bruce A., Clay, Michael P., Steinberg, Mitchell I., Bruns, Robert F., Simon, Neal G.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2067992/
https://ncbi.nlm.nih.gov/pubmed/17234419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.12.031
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料