A carregar...

Involvement of CYP 2E1 Enzyme in Ovotoxicity Caused by 4-Vinylcyclohexene and its Metabolites

4-vinylcyclohexene (VCH) is bioactivated by hepatic CYP 2A and 2B to a monoepoxide (VCM), and subsequently to an ovotoxic diepoxide metabolite (VCD). Studies suggest that the ovary can directly bioactivate VCH via CYP 2E1. The current study was designed to evaluate the role of ovarian CYP 2E1 in VCM...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rajapaksa, Kathila S., Cannady, Ellen A., Glenn Sipes, I., Hoyer, Patricia B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065846/
https://ncbi.nlm.nih.gov/pubmed/17462685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.03.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!