Loss of T cell responses following long-term cryopreservation

Although cryopreservation of peripheral blood mononuclear cells (PBMC) is a commonly used technique, the degree to which it affects subsequent functional studies has not been well defined. Here we demonstrate that long-term cryopreservation has detrimental effects on T cell IFN-γ responses in human...

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Main Authors: Owen, Rachel E., Sinclair, Elizabeth, Emu, Brinda, Heitman, John W., Hirschkom, Dale F., Epling, C. Lorrie, Tan, Qi Xuan, Custer, Brian, Harris, Jeffery M., Jacobson, Mark A., McCune, Joseph M., Martin, Jeffery N., Hecht, Frederick M., Deeks, Steven G., Norris, Philip J.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065759/
https://ncbi.nlm.nih.gov/pubmed/17707394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.07.012
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