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DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction
DNA methylation has been implicated in chromatin condensation and nuclear organization, especially at sites of constitutive heterochromatin. How this is mediated has not been clear. In this study, using mutant mouse embryonic stem cells completely lacking in DNA methylation, we show that DNA methyla...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064831/ https://ncbi.nlm.nih.gov/pubmed/17485486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200607133 |
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