Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration

The receptor tyrosine kinase Ror2 plays important roles in developmental morphogenesis. It has recently been shown that Ror2 mediates Wnt5a-induced noncanonical Wnt signaling by activating the Wnt–JNK pathway and inhibiting the β-catenin–TCF pathway. However, the function of Ror2 in noncanonical Wnt...

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Autores principales: Nishita, Michiru, Yoo, Sa Kan, Nomachi, Akira, Kani, Shuichi, Sougawa, Nagako, Ohta, Yasutaka, Takada, Shinji, Kikuchi, Akira, Minami, Yasuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064592/
https://ncbi.nlm.nih.gov/pubmed/17101698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200607127
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