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SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER

Protein quality control in the endoplasmic reticulum (ER) involves recognition of misfolded proteins and dislocation from the ER lumen into the cytosol, followed by proteasomal degradation. Viruses have co-opted this pathway to destroy proteins that are crucial for host defense. Examination of dislo...

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Bibliografiska uppgifter
Huvudupphovsmän: Mueller, Britta, Lilley, Brendan N., Ploegh, Hidde L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064567/
https://ncbi.nlm.nih.gov/pubmed/17043138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605196
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