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Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling
β Cell apoptosis and dedifferentiation are 2 hotly debated mechanisms underlying β cell loss in type 2 diabetes; however, the molecular drivers underlying such events remain largely unclear. Here, we performed a side-by-side comparison of mice carrying β cell–specific deletion of ER-associated degra...
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| Yayımlandı: | J Clin Invest |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7324191/ https://ncbi.nlm.nih.gov/pubmed/32182217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134874 |
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