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Using pyrene-labeled HIV-1 TAR to measure RNA–small molecule binding

To quantitatively understand the binding affinity and target selectivity of small-molecule RNA interactions, it is useful to have a rapid, highly reproducible binding assay that can be readily generalized to different RNA targets. To that end, an assay has been developed and validated for measuring...

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Autors principals: Blount, Kenneth F., Tor, Yitzhak
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC206455/
https://ncbi.nlm.nih.gov/pubmed/14500811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg755
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