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3′-Modified oligonucleotides by reverse DNA synthesis

Reverse DNA oligonucleotide synthesis (i.e. from 5′→3′) is a strategy that has yet to be exploited fully. While utilized previously for the construction of alternating 3′-3′- and 5′-5′-linked antisense oligonucleotides, the use of nucleoside 5′-phosphoramidites has not generally been used for the el...

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Detalhes bibliográficos
Main Authors: Claeboe, Christopher D., Gao, Rong, Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC206447/
https://ncbi.nlm.nih.gov/pubmed/14500832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg734
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