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3′-Modified oligonucleotides by reverse DNA synthesis
Reverse DNA oligonucleotide synthesis (i.e. from 5′→3′) is a strategy that has yet to be exploited fully. While utilized previously for the construction of alternating 3′-3′- and 5′-5′-linked antisense oligonucleotides, the use of nucleoside 5′-phosphoramidites has not generally been used for the el...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC206447/ https://ncbi.nlm.nih.gov/pubmed/14500832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg734 |
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