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Synthesis and biophysical analysis of modified thymine-containing DNA oligonucleotides†
We report the synthesis of a 5-formyl-2′-deoxyuridine (5fU) phosphoramidite and the preparation of oligonucleotides comprising all known, naturally observed eukaryotic thymidine modifications. Biophysical characterization of the synthetic oligonucleotides indicates that 5fU, but not the other T-deri...
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| 發表在: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5759927/ https://ncbi.nlm.nih.gov/pubmed/28074944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc08670e |
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