Modified oligonucleotides as alternatives to the synthesis of mixed probes for the screening of cDNA libraries.

Two simple alternatives to the synthesis of mixed oligodeoxyribonucleotide probes are described: mixed deblocking of triazolodeoxynucleosides for the A/G and C/T degeneracies or incorporation of 2-amino-2'-deoxyadenosines into a determined sequence for a higher stability of the hybridization du...

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Hlavní autoři: Huynh-Dinh, T, Duchange, N, Zakin, M M, Lemarchand, A, Igolen, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1985
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC390846/
https://ncbi.nlm.nih.gov/pubmed/3865174
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