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Modified oligonucleotides as alternatives to the synthesis of mixed probes for the screening of cDNA libraries.
Two simple alternatives to the synthesis of mixed oligodeoxyribonucleotide probes are described: mixed deblocking of triazolodeoxynucleosides for the A/G and C/T degeneracies or incorporation of 2-amino-2'-deoxyadenosines into a determined sequence for a higher stability of the hybridization du...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1985
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3865174/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.22.7510 |
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