Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage

Adefective response to DNA damage is observed in several human autosomal recessive ataxias with oculomotor apraxia, including ataxia-telangiectasia. We report that senataxin, defective in ataxia oculomotor apraxia (AOA) type 2, is a nuclear protein involved in the DNA damage response. AOA2 cells are...

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Bibliografiske detaljer
Main Authors: Suraweera, Amila, Becherel, Olivier J., Chen, Philip, Rundle, Natalie, Woods, Rick, Nakamura, Jun, Gatei, Magtouf, Criscuolo, Chiara, Filla, Alessandro, Chessa, Luciana, Fußer, Markus, Epe, Bernd, Gueven, Nuri, Lavin, Martin F.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064358/
https://ncbi.nlm.nih.gov/pubmed/17562789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701042
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