Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage

Adefective response to DNA damage is observed in several human autosomal recessive ataxias with oculomotor apraxia, including ataxia-telangiectasia. We report that senataxin, defective in ataxia oculomotor apraxia (AOA) type 2, is a nuclear protein involved in the DNA damage response. AOA2 cells are...

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Autors principals: Suraweera, Amila, Becherel, Olivier J., Chen, Philip, Rundle, Natalie, Woods, Rick, Nakamura, Jun, Gatei, Magtouf, Criscuolo, Chiara, Filla, Alessandro, Chessa, Luciana, Fußer, Markus, Epe, Bernd, Gueven, Nuri, Lavin, Martin F.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
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Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064358/
https://ncbi.nlm.nih.gov/pubmed/17562789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701042
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