A new model to study neurodegeneration in ataxia oculomotor apraxia type 2

Ataxia oculomotor apraxia type 2 (AOA2) is a rare autosomal recessive cerebellar ataxia. Recent evidence suggests that the protein defective in this syndrome, senataxin (SETX), functions in RNA processing to protect the integrity of the genome. To date, only patient-derived lymphoblastoid cells, fib...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mol Genet
Prif Awduron: Becherel, Olivier J., Sun, Jane, Yeo, Abrey J., Nayler, Sam, Fogel, Brent L., Gao, Fuying, Coppola, Giovanni, Criscuolo, Chiara, De Michele, Giuseppe, Wolvetang, Ernst, Lavin, Martin F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581605/
https://ncbi.nlm.nih.gov/pubmed/26231220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv296
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