DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras–ERK pathway, is required for myogenic differentiation

Ras activates Raf, leading to the extracellular-regulated kinase (ERK)–mitogen-activated protein kinase pathway, which is involved in a variety of cellular, physiological, and pathological responses. Thus, regulators of this Ras–Raf interaction play crucial roles in these responses. In this study, w...

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Detalhes bibliográficos
Main Authors: Yokoyama, Takashi, Takano, Kazunori, Yoshida, Akira, Katada, Fumiko, Sun, Peng, Takenawa, Tadaomi, Andoh, Toshiwo, Endo, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064279/
https://ncbi.nlm.nih.gov/pubmed/17535970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703195
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