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The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation

Schwann cells are a regenerative cell type. Following nerve injury, a differentiated myelinating Schwann cell can dedifferentiate and regain the potential to proliferate. These cells then redifferentiate during the repair process. This behaviour is important for successful axonal repair, but the sig...

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Detalhes bibliográficos
Main Authors: Harrisingh, Marie C, Perez-Nadales, Elena, Parkinson, David B, Malcolm, Denise S, Mudge, Anne W, Lloyd, Alison C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514926/
https://ncbi.nlm.nih.gov/pubmed/15241478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600309
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