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The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation

Schwann cells are a regenerative cell type. Following nerve injury, a differentiated myelinating Schwann cell can dedifferentiate and regain the potential to proliferate. These cells then redifferentiate during the repair process. This behaviour is important for successful axonal repair, but the sig...

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Hlavní autoři: Harrisingh, Marie C, Perez-Nadales, Elena, Parkinson, David B, Malcolm, Denise S, Mudge, Anne W, Lloyd, Alison C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC514926/
https://ncbi.nlm.nih.gov/pubmed/15241478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600309
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