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The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation

Schwann cells are a regenerative cell type. Following nerve injury, a differentiated myelinating Schwann cell can dedifferentiate and regain the potential to proliferate. These cells then redifferentiate during the repair process. This behaviour is important for successful axonal repair, but the sig...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Harrisingh, Marie C, Perez-Nadales, Elena, Parkinson, David B, Malcolm, Denise S, Mudge, Anne W, Lloyd, Alison C
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514926/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15241478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600309
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