DA-Raf-Mediated Suppression of the Ras—ERK Pathway Is Essential for TGF-β1-Induced Epithelial—Mesenchymal Transition in Alveolar Epithelial Type 2 Cells

Myofibroblasts play critical roles in the development of idiopathic pulmonary fibrosis by depositing components of extracellular matrix. One source of lung myofibroblasts is thought to be alveolar epithelial type 2 cells that undergo epithelial–mesenchymal transition (EMT). Rat RLE-6TN alveolar epit...

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Vydáno v:PLoS One
Hlavní autoři: Watanabe-Takano, Haruko, Takano, Kazunori, Hatano, Masahiko, Tokuhisa, Takeshi, Endo, Takeshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440819/
https://ncbi.nlm.nih.gov/pubmed/25996975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127888
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