Quantitative Proteomic Analysis in Alveolar Type II Cells Reveals the Different Capacities of RAS and TGF-β to Induce Epithelial–Mesenchymal Transition

Alveolar type II (ATII) epithelial cells function as stem cells, contributing to alveolar renewal, repair and cancer. Therefore, they are a highly relevant model for studying a number of lung diseases, including acute injury, fibrosis and cancer, in which signals transduced by RAS and transforming g...

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Vydáno v:Front Mol Biosci
Hlavní autoři: Zhou, Yilu, Hill, Charlotte, Yao, Liudi, Li, Juanjuan, Hancock, David, Downward, Julian, Jones, Mark G., Davies, Donna E., Ewing, Rob M., Skipp, Paul, Wang, Yihua
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Molecular Biosciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048883/
https://ncbi.nlm.nih.gov/pubmed/33869273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.595712
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