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Dominant Negative Ras Enhances Lactogenic Hormone-Induced Differentiation by Blocking Activation of the Raf-Mek-Erk Signal Transduction Pathway
EGF and Ras mitogenic signal transduction pathways are frequently activated in breast carcinoma and inhibit mammary differentiation and apoptosis. HC11 mouse mammary epithelial cells, which differentiate and synthesize β-casein following growth to confluency and stimulation with lactogenic hormones,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1586098/ https://ncbi.nlm.nih.gov/pubmed/15334659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.20077 |
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