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Dominant Negative Ras Enhances Lactogenic Hormone-Induced Differentiation by Blocking Activation of the Raf-Mek-Erk Signal Transduction Pathway
EGF and Ras mitogenic signal transduction pathways are frequently activated in breast carcinoma and inhibit mammary differentiation and apoptosis. HC11 mouse mammary epithelial cells, which differentiate and synthesize β-casein following growth to confluency and stimulation with lactogenic hormones,...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2004
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1586098/ https://ncbi.nlm.nih.gov/pubmed/15334659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.20077 |
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