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Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling

During embryonic development, cell movement is orchestrated by a multitude of attractants and repellents. Chemoattractants applied as a gradient, such as cAMP with Dictyostelium discoideum or fMLP with neutrophils, induce the activation of phospholipase C (PLC) and phosphoinositide 3 (PI3)-kinase at...

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Bibliografiske detaljer
Main Authors: Keizer-Gunnink, Ineke, Kortholt, Arjan, Van Haastert, Peter J.M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064204/
https://ncbi.nlm.nih.gov/pubmed/17517960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200611046
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