A Receptor-associated Protein/Phosphatidylinositol 3-Kinase Pathway Controls Pseudopod Formation

GbpD, a Dictyostelium discoideum guanine exchange factor specific for Rap1, has been implicated in adhesion, cell polarity, and chemotaxis. Cells overexpressing GbpD are flat, exhibit strongly increased cell-substrate attachment, and extend many bifurcated and lateral pseudopodia. Phg2, a serine/thr...

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Main Authors: Kortholt, Arjan, Bolourani, Parvin, Rehmann, Holger, Keizer-Gunnink, Ineke, Weeks, Gerald, Wittinghofer, Alfred, Van Haastert, Peter J.M.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2010
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836974/
https://ncbi.nlm.nih.gov/pubmed/20089846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-03-0177
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