Essential role of PDK1 in regulating endothelial cell migration

The serine/threonine protein kinase phosphoinositide-dependent kinase 1 (PDK1) plays a central role in cellular signaling by phosphorylating members of the AGC family of kinases, including PKB/Akt. We now present evidence showing that PDK1 is essential for the motility of vascular endothelial cells...

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Bibliographic Details
Main Authors: Primo, Luca, di Blasio, Laura, Roca, Cristina, Droetto, Sara, Piva, Roberto, Schaffhausen, Brian, Bussolino, Federico
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064087/
https://ncbi.nlm.nih.gov/pubmed/17371830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200607053
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