PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction

Directional cell migration is of paramount importance in both physiological and pathological processes, such as development, wound healing, immune response, and cancer invasion. Here, we report that 3-phosphoinositide-dependent kinase 1 (PDK1) regulates epithelial directional migration and invasion...

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Autori principali: Gagliardi, Paolo Armando, di Blasio, Laura, Puliafito, Alberto, Seano, Giorgio, Sessa, Roberto, Chianale, Federica, Leung, Thomas, Bussolino, Federico, Primo, Luca
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2014
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121984/
https://ncbi.nlm.nih.gov/pubmed/25092657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201312090
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